A parameter sensitivity study for simulating DNA damage after proton irradiation using TOPAS-nBio
نویسندگان
چکیده
منابع مشابه
SU-E-T-475: Nano-Dosimetric Track Structure Scoring including Biological Modeling with TOPAS-NBio.
PURPOSE To develop a nano-dosimetric Monte Carlo simulation package, TOPAS-nBio, based on the TOPAS (TOol for PArticle Simulations) framework that is being developed in a collaboration between the Massachusetts General Hospital (MGH), the SLAC National Accelerator Laboratory and the University of California, San Francisco. The goal is to incorporate biological processes on a sub-cell level that...
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Objective: Coronary heart disease (CHD) is one of the most common diseases. Coronary angiography (CAG) is an important apparatus used to diagnose and treat this disease. Since angiography is performed through exposure to ionizing radiation, it can cause harmful effects induced by double-stranded breaks in DNA which is potentially life-threatening damage. The aim of the present study is to inves...
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ژورنال
عنوان ژورنال: Physics in Medicine & Biology
سال: 2020
ISSN: 1361-6560
DOI: 10.1088/1361-6560/ab7a6b